Ubisoft has just released a new Q&A video, in which Assassin’s Creed: Revelations’ lead scriptwriter, Darby McDevitt, reveals the relationship between Altair and Ezio. Altair and Ezio are not in the same exact plotline and are not related directly but they come from different bloodlines. Think of it as Ezio coming from Desmond’s father side while Altair coming from Desmond’s mother side. Assassin’s Creed: Revelation is slated for a November release on X360, PS3 and hopefully PC – that is if it doesn’t get delayed at the last minute.
Assassin's Creed Revelations: Q&A #5 - Ezio & Altaïr Related? | Ubisoft [NA]