Mario fans, here is something special for you today. An unofficial native PC port of Dr. Mario 64 has just been released, allowing you to experience this Mario game natively on PC. This is a must-have for everyone who wanted to play this 2001 tile-matching action puzzle game on PC.
Dr. Mario 64 Recomp focuses on improved rendering, smoother motion, and quality-of-life enhancements while remaining faithful to the original game. Dr. Mario 64 Recomp renders the pills on the GPU instead of the CPU. Thus, it will run smoothly on a wide range of PC systems. Moreover, it has interpolation support for smooth 60+ FPS gameplay. There is 4-player controller support, as well as CRT filters.
This unofficial PC port is similar to all the other PC ports of the console-only games we’ve covered in the past. In other words, it does not contain any assets. As such, you’ll also need its ROM file, otherwise, you won’t be able to run it. To be more precise, you’ll need the US version.
For obvious reasons, we won’t allow links to the ROM file of Dr. Mario 64. So, don’t bother sharing any download links in the Comment section. If you do, your comment will be deleted. So, consider this your warning. However, I’m certain most of you will be able to find it via a simple Google search.
Those interested can go ahead and download it from this link. At the end of the article, you can also find a video for it.
In case you are into projects like these, you can also download the unofficial PC port of Super Mario 64, Mario Kart 64, Crash Team Racing, Duke Nukem: Zero Hour, The Legend of Zelda: Ocarina of Time, Majora’s Mask, Perfect Dark, Jak & Daxter, and Sonic Unleashed.
Before we wrap up, here’s something cool: a native PC port of The Legend of Zelda: Twilight Princess is now in the works. The game has already been fully decompiled. If things go well, we might see the first PC version sometime in early 2026.
Enjoy and stay tuned for more!
John is the founder and Editor in Chief at DSOGaming. He is a PC gaming fan and highly supports the modding and indie communities. Before creating DSOGaming, John worked on numerous gaming websites. While he is a die-hard PC gamer, his gaming roots can be found on consoles. John loved – and still does – the 16-bit consoles, and considers SNES to be one of the best consoles. Still, the PC platform won him over consoles. That was mainly due to 3DFX and its iconic dedicated 3D accelerator graphics card, Voodoo 2. John has also written a higher degree thesis on the “The Evolution of PC graphics cards.”
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